![]() ![]() At the end of treatment, there were no clear differences between any of these medications on any measure.Īdverse effects: Several common adverse effects (side effects) were reported by people receiving antidepressants (e.g. Two studies compared antidepressants with opioid antagonists two studies compared antidepressants with mood stabilisers and one study compared opioid antagonists and mood stabilisers. At the end of treatment, this medication was more helpful than no treatment in reducing gambling symptom severity.Ĭomparisons between medications: We identified very few studies that compared the effectiveness of different types of medications. At the end of treatment, there were no clear differences between mood stabilisers and no treatment on any measure where there was more than one available study: gambling symptom severity, depressive symptoms, or anxiety symptoms.Ītypical antipsychotics: We combined the results of two studies (63 participants) investigating the effectiveness of the atypical antipsychotic olanzapine. Mood stabilisers: We combined the results of two studies (71 participants) investigating the effectiveness of medications with mood-stabilising properties. At the end of treatment, these medications were more helpful than no treatment in improving gambling symptom severity, but there were no clear differences in terms of responder status. ![]() More than one study evaluated gambling symptom severity and responder status. Opioid antagonists: We combined the results of four studies (562 participants) investigating the effectiveness of opioid antagonists. At the end of treatment, there were no clear differences between antidepressants and no treatment on any measure where there was more than one available study: gambling symptom severity, gambling expenditure, depressive symptoms, functional impairment, or responder status. positive response to treatment based on gambling symptoms or behaviour, or both).Īntidepressants: We combined the results of six studies (268 participants) investigating the effectiveness of antidepressants. We explored the effectiveness of these treatments on a range of outcomes: gambling symptom severity, gambling expenditure, gambling frequency, depressive symptoms, anxiety symptoms, functional impairment (limitations due to the illness), and responder status (i.e. These studies compared antidepressants (medications used to prevent or treat depression), opioid antagonists (medications that reverse and block the effects of opioids like pain relievers and heroin e.g., naltrexone, nalmefene), mood stabilisers (medications that treat and prevent highs (mania) and lows (depression)), and atypical antipsychotics (medications used to treat schizophrenia or to help treat other psychiatric disorders) with either a no-treatment control group (i.e. We included 17 studies in the review with a total of 1193 participants. We included randomised trials (gold-standard trials for evaluating the effectiveness of treatments where participants are randomly assigned to one of two or more treatments) published before January 2022. placebo, or dummy treatment) or other types of medications. ![]() We investigated whether different types of medications are effective in reducing gambling symptoms compared to no treatment (i.e. A range of medications are used to treat people with gambling problems, but there are few high-quality reviews of the research evidence to guide which ones should be used in practice. ![]() Gambling problems can lead to severe consequences for gamblers, their family members and friends, and the community. ![]()
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